Joel Renick Selected Research

4- chloro- 3- (5- methyl- 3- ((4- (2- pyrrolidin- 1- ylethoxy)phenyl)amino)- 1,2,4- benzotriazin- 7- yl)phenol

1/2009	Development of novel benzotriazines for drug discovery.
3/2008	Development of prodrug 4-chloro-3-(5-methyl-3-{[4-(2-pyrrolidin-1-ylethoxy)phenyl]amino}-1,2,4-benzotriazin-7-yl)phenyl benzoate (TG100801): a topically administered therapeutic candidate in clinical trials for the treatment of age-related macular degeneration.

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Joel Renick Research Topics

Disease

2	Macular Degeneration (Age-Related Maculopathy) 01/2009 - 03/2008
2	Neoplasms (Cancer) 01/2009 - 02/2007
1	Nervous System Diseases (Neurological Disorders) 01/2020
1	Edema (Dropsy) 03/2008
1	Choroidal Neovascularization 03/2008
1	Philadelphia Chromosome 01/2008

Drug/Important Bio-Agent (IBA)

2	4- chloro- 3- (5- methyl- 3- ((4- (2- pyrrolidin- 1- ylethoxy)phenyl)amino)- 1,2,4- benzotriazin- 7- yl)phenolIBA 01/2009 - 03/2008
1	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 01/2020
1	Tirapazamine (SR 4233)IBA 01/2009
1	Benzoates (Benzoate)IBA 03/2008
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 03/2008
1	ProdrugsIBA 03/2008
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2008
1	AminesIBA 02/2007
1	src-Family KinasesIBA 02/2007

Therapy/Procedure

1	Lasers (Laser) 03/2008